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What is micellar water and how does it work?

<a href="https://theconversation.com/profiles/daniel-eldridge-1494633">Daniel Eldridge</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a> Micellar water, a product found in supermarkets, chemists and bathroom cabinets around the world, is commonly used to remove make-up. It’s a very effective cleanser and many people swear by it as part of their skincare routine. So, what is micellar water and why is it so good at getting makeup and sunscreen off? Here’s the science. <h2>What are micelles?</h2> Oil and water generally don’t mix, which is why you’ll struggle to remove makeup and sunscreen (which both contain oils) with just plain water. But micellar water products contain something called micelles – clusters of molecules that are very effective at removing oily substances. To understand why, you need to first know two chemistry terms: hydrophilic and hydrophobic. A hydrophilic substance “loves” water and mixes easily with it. Salt and sugar are examples. A hydrophobic substance “hates” water and generally refuses to mix with it. Examples include oil and wax. Hydrophilic materials will happily mix with other hydrophilic materials. The same goes for hydrophobic substances. But if you try to combine hydrophilic and hydrophobic materials, they won’t mix. <h2>How are micelles formed? It’s all about surfactants</h2> The micelles in micellar water are formed by special molecules known as surfactants. Surfactant stands for surface active agent. These molecules looked at their hydrophilic and hydrophobic brethren and said, why not both? They are typically comprised of two ends: a head group that is hydrophilic and a tail that is hydrophobic. When a small amount of surfactant is added to water, the two ends of the molecule have competing interests. The hydrophilic head wants to be in the water, but the hydrophobic tail can’t stand water. Add enough surfactant and, eventually, we will pass a critical micelle concentration and the surfactants will self-assemble into clusters of approximately 20 to 100 surfactant molecules. All the hydrophilic heads will be pointing outwards, while the hydrophobic tails remain “hidden” at the centre. These clusters are micelles. These micelles have a hydrophilic exterior, meaning that they are very happy to remain mixed throughout water. However, in the centre remains a hydrophobic pocket that’s very good at attracting oils. This is very handy, and helps explain why adding some detergent (a surfactant) to water will allow you to wash an oily saucepan. The surfactant first helps lift of the oil, and then the oil can remained mixed into the water, finding a new home in the hydrophobic centre of the micelle. <figure><iframe src="https://www.youtube.com/embed/fnRBCn8fm2o?wmode=transparent&start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> <h2>Micellar water in action</h2> Surfactants are in your dishwashing detergent, your body wash, your shampoo, your toothpaste and even many foods. In all of these cases, they are there to help the water interact with the dirt and oils, and micellar water is no different. When you apply some micellar water to a cotton pad, another convenient interaction occurs. The wet cotton is hydrophilic (loves water). Consequently, some of the micelles will unravel, with the hydrophilic heads being attracted to the wet cotton pad. Now, sticking out from the surface will be a layer of hydrophobic tail groups. These hydrophobic tails cannot wait to attract themselves to makeup, sunscreen, oils, dirt, grease and other contaminants on your face. As you sweep the cotton pad across your skin, these contaminants bind to the hydrophobic tails and are removed from the skin. Some contaminants will also find themselves encapsulated in the hydrophobic centres of the micelle. Either way, a cleaner surface is left behind. Look at how a cotton wipe soaked in micellar water cleans up a small oil spill, in comparison to water alone. <figure><iframe src="https://www.youtube.com/embed/5Nge5FEiuYE?wmode=transparent&start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> <h2>So why shouldn’t I just use dishwashing detergent to wash my face?</h2> Technically, that would work as detergent does indeed contain lots of micelle-forming surfactants. But these particular surfactants would probably cause a lot of skin and eye irritation, while also damaging and drying out your skin. Not nice. The surfactants in micellar water are chosen to be mild and well tolerated by most people’s skin. But micellar water isn’t the only skincare product to contain micelles. There are many other face-cleaning products that also make great use of surfactant molecules and work very well too. Now, it’s not perfect. While it is effective at removing a wide range of contaminants, thick or heavy makeup might not come off easily with micellar water (you might need to do a more vigorous clean). Some products say there is “zero residue”, although the fine print clearly states this refers to visible residue. Many products also state there is no rinse off required. Surfactants will remain on your skin after product use, but for many people they don’t cause irritation. If your skin is feeling irritated after using a micellar water product, you can try rinsing afterwards or discontinuing use. And as is the case with many cosmetic products, you should test it first on a small patch of skin before using it all over your face.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/219492/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/daniel-eldridge-1494633">Daniel Eldridge</a>, Senior Lecturer in Chemistry, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-micellar-water-and-how-does-it-work-219492">original article</a>.

Beauty & Style

How much weight do you actually need to lose? It might be a lot less than you think

<a href="https://theconversation.com/profiles/nick-fuller-219993">Nick Fuller</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a> If you’re one of the <a href="https://www.finder.com.au/new-years-resolutions-statistics">one in three</a> Australians whose New Year’s resolution involved losing weight, it’s likely you’re now contemplating what weight-loss goal you should actually be working towards. But type “setting a weight loss goal” into any online search engine and you’ll likely be left with more questions than answers. Sure, the many weight-loss apps and calculators available will make setting this goal seem easy. They’ll typically use a body mass index (BMI) calculator to confirm a “healthy” weight and provide a goal weight based on this range. Your screen will fill with trim-looking influencers touting diets that will help you drop ten kilos in a month, or ads for diets, pills and exercise regimens promising to help you effortlessly and rapidly lose weight. Most sales pitches will suggest you need to lose substantial amounts of weight to be healthy – making weight loss seem an impossible task. But the research shows you don’t need to lose a lot of weight to achieve health benefits. <h2>Using BMI to define our target weight is flawed</h2> We’re a society fixated on numbers. So it’s no surprise we use measurements and equations to score our weight. The most popular is BMI, a measure of our body weight-to-height ratio. BMI classifies bodies as underweight, normal (healthy) weight, overweight or obese and can be a useful tool for weight and health screening. But it shouldn’t be used as the single measure of what it means to be a healthy weight when we set our weight-loss goals. This is <a href="https://theconversation.com/using-bmi-to-measure-your-health-is-nonsense-heres-why-180412">because</a> it: <ul> <li> fails to consider two critical factors related to body weight and health – body fat percentage and distribution </li> <li> does not account for significant differences in body composition based on gender, ethnicity and age. </li> </ul> <h2>How does losing weight benefit our health?</h2> Losing just 5–10% of our body weight – between 6 and 12kg for someone weighing 120kg – can significantly improve our health in four key ways. 1. Reducing cholesterol Obesity increases the chances of having too much low-density lipoprotein (LDL) cholesterol – also known as bad cholesterol – because carrying excess weight changes how our bodies produce and manage lipoproteins and triglycerides, another fat molecule we use for energy. Having too much bad cholesterol and high triglyceride levels is not good, narrowing our arteries and limiting blood flow, which increases the risk of heart disease, heart attack and stroke. But <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987606/">research</a> shows improvements in total cholesterol, LDL cholesterol and triglyceride levels are evident with just 5% weight loss. 2. Lowering blood pressure Our blood pressure is considered high if it reads more than 140/90 on at least two occasions. Excess weight is <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082272/">linked to</a> high blood pressure in <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082272/">several ways</a>, including changing how our sympathetic nervous system, blood vessels and hormones regulate our blood pressure. Essentially, high blood pressure makes our heart and blood vessels work harder and less efficiently, damaging our arteries over time and increasing our risk of heart disease, heart attack and stroke. Like the improvements in cholesterol, a 5% weight loss <a href="https://onlinelibrary.wiley.com/doi/10.1002/oby.21358">improves</a> both systolic blood pressure (the first number in the reading) and diastolic blood pressure (the second number). A <a href="https://www.ahajournals.org/doi/10.1161/01.hyp.0000094221.86888.ae">meta-analysis of 25 trials</a> on the influence of weight reduction on blood pressure also found every kilo of weight loss improved blood pressure by one point. 3. Reducing risk for type 2 diabetes Excess body weight is the primary manageable risk factor for type 2 diabetes, particularly for people carrying a lot of visceral fat around the abdomen (belly fat). Carrying this excess weight can cause fat cells to release pro-inflammatory chemicals that disrupt how our bodies regulate and use the insulin produced by our pancreas, leading to high blood sugar levels. Type 2 diabetes can lead to serious medical conditions if it’s not carefully managed, including damaging our heart, blood vessels, major organs, eyes and nervous system. <a href="https://www.nejm.org/doi/full/10.1056/nejmoa012512">Research</a> shows just 7% weight loss reduces risk of developing type 2 diabetes by 58%. 4. Reducing joint pain and the risk of osteoarthritis Carrying excess weight can cause our joints to become inflamed and damaged, making us more prone to osteoarthritis. <a href="https://pubmed.ncbi.nlm.nih.gov/21425246/">Observational studies</a> show being overweight doubles a person’s risk of developing osteoarthritis, while obesity increases the risk fourfold. Small amounts of weight loss alleviate this stress on our joints. <a href="https://pubmed.ncbi.nlm.nih.gov/15986358/">In one study</a> each kilogram of weight loss resulted in a fourfold decrease in the load exerted on the knee in each step taken during daily activities. <h2>Focus on long-term habits</h2> If you’ve ever tried to lose weight but found the kilos return almost as quickly as they left, you’re not alone. An <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764193/">analysis</a> of 29 long-term weight-loss studies found participants regained more than half of the weight lost within two years. Within five years, they regained more than 80%. When we lose weight, we take our body out of its comfort zone and trigger its survival response. It then counteracts weight loss, triggering several <a href="https://pubmed.ncbi.nlm.nih.gov/25896063/">physiological responses</a> to defend our body weight and “survive” starvation. Just as the problem is evolutionary, the solution is evolutionary too. Successfully losing weight long-term comes down to: <ul> <li> losing weight in small manageable chunks you can sustain, specifically periods of weight loss, followed by periods of weight maintenance, and so on, until you achieve your goal weight </li> <li> making gradual changes to your lifestyle to ensure you form habits that last a lifetime. </li> </ul> Setting a goal to reach a healthy weight can feel daunting. But it doesn’t have to be a pre-defined weight according to a “healthy” BMI range. Losing 5–10% of our body weight will result in immediate health benefits. At the Boden Group, Charles Perkins Centre, we are studying the science of obesity and running clinical trials for weight loss. You can <a href="https://redcap.sydney.edu.au/surveys/?s=RKTXPPPHKY">register here</a> to express your interest.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/217287/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/nick-fuller-219993">Nick Fuller</a>, Charles Perkins Centre Research Program Leader, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/how-much-weight-do-you-actually-need-to-lose-it-might-be-a-lot-less-than-you-think-217287">original article</a>.

Body

Trying to spend less on food? Following the dietary guidelines might save you $160 a fortnight

<a href="https://theconversation.com/profiles/emily-burch-438717">Emily Burch</a>, <a href="https://theconversation.com/institutions/southern-cross-university-1160">Southern Cross University</a> and <a href="https://theconversation.com/profiles/lauren-ball-14718">Lauren Ball</a>, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> A rise in the <a href="https://www.aph.gov.au/About_Parliament/Parliamentary_departments/Parliamentary_Library/pubs/BriefingBook47p/CostOfLiving#:%7E:text=Consumer%20Price%20Index%20over%20time,but%205.1%25%20in%20the%20second">cost of living</a> has led many households to look for ways to save money. New research suggests maintaining a healthy diet, in line with the <a href="https://www.eatforhealth.gov.au/guidelines/guidelines">Australian Dietary Guidelines</a>, is cheaper than an unhealthy diet and <a href="https://southwesthealthcare.com.au/wp-content/uploads/SWH-HP-Healthy-Diets-ASAP-Protocol-Warrnambool-Report-2023.pdf">could save A$160</a> off a family of four’s fortnightly shopping bill. Poor diet is the most common preventable risk factor contributing to chronic disease in <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30752-2/fulltext">Australia</a>. So improving your diet can also be an important way to reduce the chance of developing chronic disease. <h2>First, what are the dietary guidelines?</h2> The guidelines provide information on the quantity and types of foods most Australians should consume to promote overall health and wellbeing. Recommendations include eating a wide variety of nutritious foods from the main five food groups: <ul> <li>vegetables and legumes</li> <li>fruit</li> <li>grains</li> <li>lean meats and meat alternatives such as tofu, nuts and legumes</li> <li>dairy products.</li> </ul> The guidelines recommend limiting our intake of foods high in saturated fat, added salt, added sugars and alcohol. <h2>What are Australians eating?</h2> Fewer than <a href="https://www.abs.gov.au/statistics/health/health-conditions-and-risks/dietary-behaviour/latest-release">7%</a> of Australians eat sufficient vegetables, in line with the Australian Dietary Guidelines. In fact, Australians have an average healthy diet score of <a href="https://www.csiro.au/-/media/News-releases/2023/Total-Wellbeing-Diet-Health-Score/Diet-score-2023-Report_September.pdf">55 out of 100</a> – barely passing. Foods that aren’t part of a food group are known as “discretionary” items, which includes alcohol, cakes, biscuits, chocolate and confectionery and most takeaway foods. Because they’re typically high in kilojoules, saturated fat, sodium and added sugars, the Australian Dietary Guidelines recommend they only be eaten occasionally and in small amounts (ideally zero serves). For many households, discretionary items make up a big portion of their grocery shop. Australians consume an average of <a href="https://www.csiro.au/-/media/News-releases/2023/Total-Wellbeing-Diet-Health-Score/Diet-score-2023-Report_September.pdf">28 serves</a> of discretionary choices per week (equal to 28 doughnuts, 28 slices of cake, or 28 cans of soft drink or beer). This is an increase of ten serves since 2015. One recent <a href="https://link.springer.com/article/10.1186/s12966-022-01389-8">study</a> estimated 55% of Australians’ total energy intake was from discretionary items. <h2>What did the researchers find?</h2> Researchers from the Health Promotion Team at South West Healthcare <a href="https://southwesthealthcare.com.au/wp-content/uploads/SWH-HP-Healthy-Diets-ASAP-Protocol-Warrnambool-Report-2023.pdf">recently</a> visited four local supermarkets and takeaway stores in Warrnambool, Victoria, and purchased two baskets of groceries. One basket met the Australian Dietary Guidelines (basket one), the other aligned with the typical dietary intake of Australians (basket two). They compared prices between the two and found basket one would cost approximately $167 less per fortnight for a family of four at the most affordable supermarket. That’s equal to $4,342 a year. Basket one was sufficient to supply a family of four for a fortnight, and aligned with the Australian Dietary Guidelines. It cost $724 and included: <ol> <li>fruit and vegetables (made up 31% of the fortnightly shop)</li> <li>grains and cereals (oats, cornflakes, bread, rice, pasta, Weet-bix)</li> <li>lean meats and alternatives (mince, steak, chicken, tuna, eggs, nuts)</li> <li>milk, yoghurt and cheese</li> <li>oils and spreads (olive oil).</li> </ol> Basket two reflected the current average Australian fortnightly shop for a family of four. In the project, the team spent over half of the fortnightly shop on processed and packaged foods, of which 21% was spent on take-away. This is based on actual dietary intake of the general population reported in the 2011-2012 <a href="https://www.abs.gov.au/statistics/health/health-conditions-and-risks/australian-health-survey-nutrition-first-results-foods-and-nutrients/latest-release#:%7E:text=Food%20consumption,across%20the%20major%20food%20groups.">Australian Health Survey</a>. Basket two cost $891 and included: <ol> <li>fruit and vegetables (made up 13% of the fortnightly shop)</li> <li>grains and cereals (oats, cornflakes, bread, rice, pasta, Weet-bix)</li> <li>lean meats and alternatives (mince, steak, chicken, tuna, eggs, nuts)</li> <li>milk, yogurt and cheese</li> <li>oils and spreads (olive oil, butter)</li> <li>drinks (soft drink, fruit juice)</li> <li>desserts and snacks (muffins, sweet biscuits, chocolate, ice cream, potato chips, muesli bars)</li> <li>processed meats (sausages, ham)</li> <li>convenience meals</li> <li>fast food (pizza, meat pie, hamburger, fish and chips)</li> <li>alcohol (beer, wine).</li> </ol> <h2>But a healthy basket is still unaffordable for many</h2> While this piece of work, and other <a href="https://www.mdpi.com/1660-4601/15/11/2469">research</a>, suggests a healthy diet is less expensive than an unhealthy diet, affordability is still a challenge for many families. The Warrnambool research found basket one (which aligned with guidelines) was still costly, requiring approximately 25% of a median household income. This is unaffordable for many. For a household reliant on welfare, basket one would require allocating 26%-38% of their income. This highlights how the rising cost of living crisis is affecting those already facing financial difficulties. Around 3.7 <a href="https://reports.foodbank.org.au/foodbank-hunger-report-2023/">million</a> Australian households did not have access to enough food to meet their basic needs at some point in the last 12 months. Policy action is needed from the Australian government to make recommended diets more affordable for low socioeconomic groups. This means lowering the costs of healthy foods and ensuring household incomes are sufficient. <h2>What else can you do to cut your spending?</h2> To help reduce food costs and support your health, reducing discretionary foods could be a good idea. Other ways to reduce your grocery bill and keep your food healthy and fresh include: <ul> <li> planning for some meatless meals each week. Pulses (beans, lentils and legumes) are nutritious and cheap (a can is <a href="https://coles.com.au/product/coles-chick-peas-420g-8075852?uztq=46abcbb7e16253b0cdc3e6c5bbe6a3f0&cid=col_cpc_Generic%7cColesSupermarkets%7cPLA%7cCatchAll%7cAustralia%7cBroad&s_kwcid=AL!12693!3!675842378376!!!g!326304616489!&gad_source=1&gclid=CjwKCAjwkY2qBhBDEiwAoQXK5SceYhU2VtKepNLXWN218GH8Cp8Vs9cnYynCBwRqQPaW3UYNX2SVIBoC_6EQAvD_BwE&gclsrc=aw.ds">less than $1.50</a>. Here are some great pulse recipes to <a href="https://nomoneynotime.com.au/healthy-easy-recipes/filter/keywords--vegetarian/p2">try</a> </li> <li> checking the specials and buy in bulk (to store or freeze) when items are cheaper </li> <li> making big batches of meals and freezing them. Single-serve portions can help save time for lunches at work, saving on takeaway </li> <li> Australian supermarkets are <a href="https://www.theguardian.com/australia-news/datablog/2023/jul/27/cost-of-living-grocery-store-price-rises-cheapest-fresh-produce-australia-woolworths-coles#:%7E:text=The%20results%20showed%20independent%20and,best%20place%20for%20affordable%20groceries">almost never</a> the cheapest place for fresh produce, so shop around for farmers markets or smaller local grocery shops </li> <li> buying generic brands when possible, as they are <a href="https://www.cambridge.org/core/journals/public-health-nutrition/article/streamlined-datagathering-techniques-to-estimate-the-price-and-affordability-of-healthy-and-unhealthy-diets-under-different-pricing-scenarios/872EA6396533166E0C6FA94C809D9CAC#r">notably cheaper</a>. Supermarkets usually <a href="https://theconversation.com/the-science-that-makes-us-spend-more-in-supermarkets-and-feel-good-while-we-do-it-23857">promote</a> the items they want you to buy at eye-level, so check the shelves above and below for cheaper alternatives.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/216749/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> </li> </ul> <a href="https://theconversation.com/profiles/emily-burch-438717">Emily Burch</a>, Dietitian & Academic, <a href="https://theconversation.com/institutions/southern-cross-university-1160">Southern Cross University</a> and <a href="https://theconversation.com/profiles/lauren-ball-14718">Lauren Ball</a>, Professor of Community Health and Wellbeing, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/trying-to-spend-less-on-food-following-the-dietary-guidelines-might-save-you-160-a-fortnight-216749">original article</a>.

Food & Wine

Eye-watering price tag for "remarkable" first class Titanic menu

A first class dinner menu from the Titanic has been found and sold at an auction in England for £84,000 (around $162,000 AUD) on November 11. The water-stained menu was dated April 11, 1912 just three days before the ship hit an iceberg, ultimately meeting it's ill-fated end causing over 1500 deaths. Wealthy passengers at the time were spoiled with choice, with oysters, salmon, beef, squab (baby pigeon), spring lamb among other dishes on the menu, and that's not including dessert. Auctioneers Henry Aldridge & Son said it was unclear how the menu made it off the ship intact, but the slight water damage suggests that it was recovered from the body of a victim. The rare artefact, which is over 111 years old belonged to amateur historian Len Stephenson, from Nova Scotia, Canada, who passed away in 2017. No one knew he had it, including his family, who only discovered it after going through his belongings following his death. “About six months ago his daughter and his son-in-law, Allen, felt the time was right to go through his belongings,” auctioneer Andrew Aldridge said. “As they did they found this menu in an old photo album. “Len was a very well thought-of historian in Nova Scotia which has strong connections with the Titanic. The body recovery ships were from Nova Scotia and so all the victims were taken back there. “Sadly, Len has taken the secret of how he acquired this menu to the grave with him.” Stephenson worked at a post office and would talk to people, collect old pictures and write letters for them, which might be how he got the rare artefact. According to the auctioneer, no other first class dinner menus dated April 11, 1912 have been recovered from the titanic making this “a remarkable survivor from the most famous Ocean liner of all time”. “There are a handful of April 14 menus in existence but you just don’t see menus from April 11. Most of them would have gone down with the ship,” Aldridge said. “Whereas with April 14 menus, passengers would have still had them in their coat and jacket pockets from earlier on that fateful night and still had them when they were taken off the ship," he added. A few other items recovered from the Titanic were also sold, including a Swiss-made pocket watch recovered from passenger Sinai Kantor which fetched £97,000 (around $187,000 AUD). A tartan-patterned deck blanket, which was likely used during the rescue operation also sold for £96,000 (around $185,000). Images: Henry Aldridge & Son of Devizes, Wiltshire

Cruising

Does running water really trigger the urge to pee? Experts explain the brain-bladder connection

<a href="https://theconversation.com/profiles/james-overs-1458017">James Overs</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a> We all know that feeling when nature calls – but what’s far less understood is the psychology behind it. Why, for example, do we get the urge to pee just before getting into the shower, or when we’re swimming? What brings on those “nervous wees” right before a date? Research suggests our brain and bladder are in constant communication with each other via a neural network called the <a href="https://www.einj.org/journal/view.php?doi=10.5213/inj.2346036.018">brain-bladder axis</a>. This complex web of circuitry is comprised of sensory neural activity, including the sympathetic and parasympathetic nervous systems. These neural connections allow information to be sent <a href="https://doi.org/10.3390/diagnostics12123119">back and forth</a> between the brain and bladder. The brain-bladder axis not only facilitates the act of peeing, but is also responsible for telling us we need to go in the first place. <h2>How do we know when we need to go?</h2> As the bladder fills with urine and expands, this activates special receptors detecting stretch in the nerve-rich lining of the bladder wall. This information is then relayed to the “periaqueductal gray” – a part of the brain in the brainstem which <a href="https://www.nature.com/articles/nrn2401">constantly monitors</a> the bladder’s filling status. <figure class="align-center zoomable"><a href="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=1000&fit=clip"><img src="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=600&h=454&fit=crop&dpr=1 600w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=600&h=454&fit=crop&dpr=2 1200w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=600&h=454&fit=crop&dpr=3 1800w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=45&auto=format&w=754&h=570&fit=crop&dpr=1 754w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=30&auto=format&w=754&h=570&fit=crop&dpr=2 1508w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&q=15&auto=format&w=754&h=570&fit=crop&dpr=3 2262w" alt="" /></a><figcaption>The periaqueductal gray is a section of gray matter located in the midbrain section of the brainstem. <a class="source" href="https://en.wikipedia.org/wiki/Brainstem#/media/File:1311_Brain_Stem.jpg">Wikimedia/OpenStax</a>, <a class="license" href="http://creativecommons.org/licenses/by-sa/4.0/">CC BY-SA</a></figcaption></figure> Once the bladder reaches a certain threshold (roughly 250-300ml of urine), another part of the brain called the “pontine micturition centre” is activated and signals that the bladder needs to be emptied. We, in turn, <a href="https://pubmed.ncbi.nlm.nih.gov/16254993/">register this</a> as that all-too-familiar feeling of fullness and pressure down below. Beyond this, however, a range of situations can trigger or exacerbate our need to pee, by increasing the production of urine and/or stimulating reflexes in the bladder. <h2>Peeing in the shower</h2> If you’ve ever felt the need to pee while in the shower (no judgement here) it may be due to the sight and sound of running water. In a 2015 study, <a href="https://doi.org/10.1371/journal.pone.0126798">researchers demonstrated</a> that males with urinary difficulties found it easier to initiate peeing when listening to the sound of running water being played on a smartphone. Symptoms of overactive bladder, including urgency (a sudden need to pee), have also been <a href="https://www.alliedacademies.org/articles/environmental-cues-to-urgency-and-incontinence-episodes-in-chinesepatients-with-overactive-urinary-bladder-syndrome.html">linked to</a> a range of environmental cues involving running water, including washing your hands and taking a shower. This is likely due to both physiology and psychology. Firstly, the sound of running water may have a relaxing physiological effect, increasing activity of the parasympathetic nervous system. This would relax the bladder muscles and prepare the bladder for emptying. At the same time, the sound of running water may also have a conditioned psychological effect. Due to the countless times in our lives where this sound has coincided with the actual act of peeing, it may trigger an instinctive reaction in us to urinate. This would happen in the same way <a href="https://www.simplypsychology.org/pavlov.html">Pavlov’s dog learnt</a>, through repeated pairing, to salivate when a bell was rung. <h2>Cheeky wee in the sea</h2> But it’s not just the sight or sound of running water that makes us want to pee. Immersion in cold water has been shown to cause a “cold shock response”, <a href="https://pubmed.ncbi.nlm.nih.gov/19945970">which activates</a> the sympathetic nervous system. This so-called “fight or flight” response drives up our blood pressure which, in turn, causes our kidneys to filter out more fluid from the bloodstream to stabilise our blood pressure, in a process called “<a href="https://link.springer.com/article/10.1007/BF00864230">immersion diuresis</a>”. When this happens, our bladder fills up faster than normal, triggering the urge to pee. Interestingly, immersion in very warm water (such as a relaxing bath) may also increase urine production. In this case, however, it’s due to activation of the parasympathetic nervous system. <a href="https://doi.org/10.1007/s004210050065">One study</a> demonstrated an increase in water temperature from 40℃ to 50℃ reduced the time it took for participants to start urinating. Similar to the effect of hearing running water, the authors of the study suggest being in warm water is calming for the body and activates the parasympathetic nervous system. This activation can result in the relaxation of the bladder and possibly the pelvic floor muscles, bringing on the urge to pee. <h2>The nervous wee</h2> We know stress and anxiety can cause bouts of nausea and butterflies in the tummy, but what about the bladder? Why do we feel a sudden and frequent urge to urinate at times of heightened stress, such as before a date or job interview? When a person becomes stressed or anxious, the body goes into fight-or-flight mode through the activation of the sympathetic nervous system. This triggers a cascade of physiological changes designed to prepare the body to face a perceived threat. As part of this response, the muscles surrounding the bladder may contract, leading to a more urgent and frequent need to pee. Also, as is the case during immersion diuresis, the increase in blood pressure associated with the stress response may <a href="https://doi.org/10.1172/JCI102496">stimulate</a> the kidneys to produce more urine. <h2>Some final thoughts</h2> We all pee (most of us several times a day). Yet <a href="https://doi.org/10.5489/cuaj.1150">research has shown</a> about 75% of adults know little about how this process actually works – and even less about the brain-bladdder axis and its role in urination. <a href="https://www.continence.org.au/about-us/our-work/key-statistics-incontinence#:%7E:text=Urinary%20incontinence%20affects%20up%20to,38%25%20of%20Australian%20women1.">Most Australians</a> will experience urinary difficulties at some point in their lives, so if you ever have concerns about your urinary health, it’s extremely important to consult a healthcare professional. And should you ever find yourself unable to pee, perhaps the sight or sound of running water, a relaxing bath or a nice swim will help with getting that stream to flow.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/210808/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/james-overs-1458017">James Overs</a>, Research Assistant, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, Urology Research Registrar, Western Health, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, Professor, University of Melbourne, Department of Surgery. President Urological Society Australia and New Zealand, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, Associate Professor and Clinical Psychologist, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/does-running-water-really-trigger-the-urge-to-pee-experts-explain-the-brain-bladder-connection-210808">original article</a>.

Mind

Princess Diana's dresses fetch an eye-watering sum at auction

Three dresses worn by Princess Diana have sold for $2.5 million (AUD) at an auction in Beverly Hills, California. The gowns were sold in a Legends: Hollywood And Royalty sale, by Julien's Auctions and featured over 1,400 items to celebrate 100 years of Warner Bros. All three dresses sold for six-figures, with one selling for almost triple it's estimated price. Martin Nolan, the executive director, said the record-breaking sale of Diana's dresses "exceeded all expectations". Princess Diana's black and jade gown was the most expensive item, selling for $895,580. The dress was made by Catherine Walker - her personal designer for over 16 years - which she wore to a gala event in Toronto, Canada, in October 1991. The second most expensive dress sold was a red silk dress made by Bruce Oldfield, which she wore to the premiere of Hot Shots at the Odeon Leicester Square the following month. The Oldfield dress fetched a stunning $895,547 - which was almost triple it's estimated $312,000 price tag. The final dress was a custom-made black velvet and ivory gown Diana wore to a private function, which was also designed by Walker, and fetched $796,070. The original price of the velvet and ivory gown was estimated to be around $93,000 - $125,000. The three dresses have not been seen in public for over 30 years, according to the auction house. They were originally bought by American businesswoman Ellen Petho, who bought five of Princess Diana's dresses for $234,000 at an auction in New York. Petho, who passed away in January aged 82, ended up only keeping three of the dresses, which her husband has now sold to help raise money for a scholarship fund for mature art and design students in memory of his wife. Petho's daughter Karrie, told the Mail: "Our mother read the inscription inside [the auction catalogue] about Prince William telling his mother that the dresses should not sit in her closet, that they should be out in the world and doing good. I think that's what inspired her." Image: Brian Lawless/PA Images via Getty Images

Beauty & Style

The cost of living is biting. Here’s how to spend less on meat and dairy

Food & Wine

Fleetwood Mac legend’s eye-watering fortune revealed

Fleetwood Mac star Christine McVie left behind a $135 million fortune, probate documents revealed. The singer and keyboardist <a href="https://www.oversixty.com.au/news/news/there-are-no-words-fleetwood-mac-star-dies-aged-79" target="_blank" rel="noopener">passed away aged 79</a> in November last year following a short illness. McVie, who was living in London at the time, had suffered a <a href="https://www.oversixty.com.au/health/caring/fleetwood-mac-star-s-cause-of-death-revealed" target="_blank" rel="noopener">stroke and had cancer</a>. A year before her death, she secured a massive deal and sold the rights to her entire back catalogue of 115 songs. McVie played in several bands before joining Fleetwood Mac in 1970, just two years after she married the band’s bassist John McVie. She left the band in 1998 and returned to tour in 2014. Following her death, her former bandmates Mick Fleetwood and Stevie Nicks said: “She was truly one of a kind, special and talented beyond measure. “She was the best musician anyone could have in their band and the best friend anyone could have in their life. “We were so lucky to have a life with her. Individually and together, we cherished Christine deeply and are thankful for the amazing memories we have. “She will be so very missed.” In February this year, Fleetwood admitted that the band was most likely “done” for good following McVie’s death. "I think right now, I truly think the line in the sand has been drawn with the loss of Chris," he told the Los Angeles Times. "I'd say we're done, but then we've all said that before. It's sort of unthinkable right now." Image: Instagram

Money & Banking

"Get out of the water!" Huge shark spotted at crowded beach

Dramatic footage has revealed the moment a shark was spotted swimming in shallow waters at a crowded beach in Florida. In the video filmed at Navarre beach on Monday, a sizeable fin can be spotted zipping past swimmers as panicked onlookers screamed for them to get out. "Get out of the water!" one person screamed, as stunned swimmers ran for their lives. However there was an eerie lack of urgency for a few others who took their time exiting the waters, with no worries whatsoever to the frustration of a bystander who commented: "They're still out there." Cristy Cox, who filmed the footage, told the Pensacola News Journal that the shark was simply chasing a fish, but warned people to be aware of their surroundings. “It all happened so fast! A dolphin was actually side by side with the shark at first and then just disappeared,” she said. “The shark was just trying to feed as they are expected and just passed by swimmers. “Everyone was stunned as it moved down the beach chasing the school of fish. We all just have to remember this is natural and we are in their home, so stay alert!” Beach Safety Director Austin Turnbill confirmed to the publication that a shark had been spotted at the beach, but for people to not be alarmed. “There’s sharks in the Gulf, everywhere. We see sharks almost every day and there’s nothing to be alarmed of for 99.9% of the time,” he said. Image: Cristy Cox Facebook

Travel Trouble

Five easy ways to use less water at home – and not just in a drought

<a href="https://theconversation.com/profiles/niko-wanders-1234321">Niko Wanders</a>, <a href="https://theconversation.com/institutions/utrecht-university-1354">Utrecht University</a> With so much of the world suffering from drought, you might think your ability to help is minimal. But when you consider the average person in the UK uses around <a href="https://www.water.org.uk/news-item/vast-majority-of-brits-have-no-idea-how-much-water-they-use-each-day/">142 litres of water a day</a>, it’s easy to see how small changes to your routine can add up. More than half of the water that is extracted from rivers, streams and aquifers in the UK feeds the <a href="https://www.gov.uk/government/statistical-data-sets/env15-water-abstraction-tables">public water supply</a>. These abstractions, as they’re called, worsen drought conditions by draining local waterways, depriving vegetation, fish and other aquatic life of the water they need to survive droughts. Filling paddling pools to cool off, taking multiple showers each day to stay clean, watering the garden to revive wilting plants – all these extra activities contribute to a sharp increase in public water use on hot and dry days. And these impacts can endure for months, as freshwater systems need a lot of additional rainfall to recover from droughts. If each person can reduce their water use during a drought, it would significantly benefit the natural world in its recovery. Here are five things you can do, starting today. <h2>1. Shower less</h2> Most of the water you use is <a href="https://www.water.org.uk/news-item/vast-majority-of-brits-have-no-idea-how-much-water-they-use-each-day/">in the shower</a>. For every minute you’re under the shower head (depending on how powerful it is), around 10 litres of water drains away. Since most people shower for <a href="https://www.mirashowers.co.uk/blog/trends/revealed-what-brits-are-really-getting-up-to-in-the-bathroom-1/#:%7E:text=Most%20Brits%20(62%25)%20bathe,latest%20UK%20shower%20habits%20survey.">an average of seven minutes</a>, half of your daily water use takes place first thing in the morning. Turning off the shower while shampooing your hair or applying shower gel can help conserve water, as can shortening the length of your shower overall. Be sure not to switch to a bath though – the average soak in the tub uses <a href="https://www.water.org.uk/news-item/vast-majority-of-brits-have-no-idea-how-much-water-they-use-each-day/">around 80 litres of water</a>. <h2>2. Use rainwater in the garden</h2> <figure class="align-right zoomable"><figcaption></figcaption></figure> During a dry spell, the average gardener can use <a href="https://www.southwestwater.co.uk/siteassets/documents/uwu-0618-web-version.pdf">hundreds of litres</a> of water to keep their plants hydrated. Some people will use a watering can (good), others might leave a sprinkler on all day (bad). Most use drinking water, which is a waste – plants are happy with rain water. Add a water butt that collects the rain which falls on your roof and use it for the garden. To find out how to install one, <a href="https://www.youtube.com/watch?v=2jk0lstsu5o">watch this</a>. <h2>3. Use the short flush</h2> Per flush, your toilet uses about <a href="https://www.water.org.uk/news-item/vast-majority-of-brits-have-no-idea-how-much-water-they-use-each-day/">5 litres of water</a>, and up to 10 litres in older models. If available, use the short flush to significantly reduce how much water is wasted. <h2>4. Cut back on car washing</h2> If you need to wash your car, do it the old-fashioned way with a bucket and soap rather than hosing it down. The water contained in a bucket (<a href="https://www.water.org.uk/news-item/vast-majority-of-brits-have-no-idea-how-much-water-they-use-each-day/">roughly 30 litres</a>) is significantly less than the average that flows through a hose (around <a href="https://www.southwestwater.co.uk/siteassets/documents/uwu-0618-web-version.pdf">15 litres per minute</a>). Better yet, avoid washing your car entirely during a drought. <h2>5. Reuse water</h2> If you’re washing vegetables, you could collect the water in a bowl in the sink and later give it to the plants in your house or outside. While you’re waiting for warm water to come out of a tap, use the cold to fill the kettle. Close the tap while you’re lathering your hands with soap or brushing your teeth. Though these are only small savings, they do make a difference over time. Inflatable pools are lovely for cooling down on the hottest days. A cleaning pump can filter the water and recycle it without you needing to use more water to keep the pool clean. <h2>Save water, save money</h2> All these tips can significantly reduce your water use and combat the effects of drought on the environment. They can also save you money. If you’re able to renovate your home, it’s worth installing a system for collecting rain water which, combined with a pump, can flush toilets. In Belgium, for example, it is common practice to have such a system installed (effectively, a large underground water butt) in newly built houses. Most people would struggle to afford these kinds of measures, and so drought-proofing homes and communities should be part of the effort to adapt countries to the extreme weather expected in a rapidly warming world. Image credit: Shutterstock <hr /> <figure class="align-right "><figcaption></figcaption></figure> Don’t have time to read about climate change as much as you’d like? <a href="https://theconversation.com/uk/newsletters/imagine-57?utm_source=TCUK&utm_medium=linkback&utm_campaign=Imagine&utm_content=DontHaveTimeTop">Get a weekly roundup in your inbox instead.</a> Every Wednesday, The Conversation’s environment editor writes Imagine, a short email that goes a little deeper into just one climate issue. <a href="https://theconversation.com/uk/newsletters/imagine-57?utm_source=TCUK&utm_medium=linkback&utm_campaign=Imagine&utm_content=DontHaveTimeBottom">Join the 10,000+ readers who’ve subscribed so far.</a><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/187885/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <hr /> <a href="https://theconversation.com/profiles/niko-wanders-1234321">Niko Wanders</a>, Assistant Professor in Hydrological Extremes, <a href="https://theconversation.com/institutions/utrecht-university-1354">Utrecht University</a> This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/five-easy-ways-to-use-less-water-at-home-and-not-just-in-a-drought-187885">original article</a>.

Home & Garden

King Charles’ eye-watering net worth revealed

The royal family’s net worth has always been up for speculation, but The Times has analysed the King’s various income streams and unveiled the King’s personal net worth. King Charles reportedly has a personal net worth of £600 million or around $1.1 billion. The King’s fortune surpasses the late Queen’s net wealth of £370 million or $684 million, by more than double the amount. A former aide told The Times that King Charles had managed to accumulate a significant net wealth over the years following his costly divorce from Princess Diana in 1996 - where he paid her a $31 million lump sum and $740,000 annual salary. “He became prudent at tucking away some money from the Duchy [of Cornwall] after that wipe-out [of capital],” said the source. The duchy is where most of King Charles’ income comes from. There are two duchies in the UK, the Duchy of Lancaster and the Duchy of Cornwall. Both of these property empires primarily invest in land. King Charles inherited the Duchy of Lancaster following his mother’s death last September, and Prince William is now in charge of overseeing the Duchy of Cornwall, which is estimated to be worth $1.8 billion. When King Charles was in charge of overseeing the Duchy of Cornwall, he had increased its annual profits by 42.6 per cent to $47 million between 2011-2022. He made $393.6 million from the duchy in that time period, which isn’t liable to tax, though King has been voluntarily paying income tax since 1993. A lot of the revenue comes from “renting commercial properties” from other parts of the UK according to The Times. The Duchy of Lancaster has $1.2 billion of net assets, and although the royal in charge of overseeing the duchies are not allowed to sell the assets, they can keep the annual revenue. Sandringham and Balmoral are a couple of other income streams for King Charles, with an estimated value of $453 million for Sandringham and $388 million for the Balmoral castle and its estate. Image: Getty

Money & Banking

Why smart people prefer fewer friends

While we know that loneliness can be bad for our health, it seems that not everyone wants to be surrounded by a big group of friends. For those with a higher IQ, in fact, a smaller circle of friends is preferred. <a href="http://www.ncbi.nlm.nih.gov/pubmed/26847844">In their study of wellbeing</a> published in the British Journal of Psychology, researchers looked at what it is that makes people happy. Using a group of 15,000 people aged 18 to 28, they found that those living in more densely populated areas deemed themselves a being less satisfied with their quality of life. They then looked at the number of interactions the people had with their inner circle of friends, and it appeared that the more connections they made, the happier they reported being. However there was a significant exception to this ‘more is better’ approach to friendship. For those with the highest IQs, the correlation went the other way – they were less likely to claim to be satisfied with their quality of life if they were interacting with their friendship group more often. Does this sound familiar? Do you know some very smart people (or you may even be the smart one) who prefer to spend time on their own rather than being out and about with friends? It seems that for the super intelligent, spending time socialising can be seen as a missed opportunity to better oneself. Meaning that instead of going to a party or a film, they would prefer to spend time studying, reading, or partaking in activities that will help them achieve their own personal goals. These are the people who would stay home to study when everyone else was going on a road trip for the weekend. The person who started their own business and spent every spare minute they had on it. They would even miss special occasions as they were so caught up in what they were doing that they didn’t notice the time. So if you are on the receiving end of a ‘no thank you’ to your invitation to socialise from your high IQ pal, now you know not to take it personally. It’s not that they don’t see friendship as valuable and important, they just really value their own time and space to try and reach their goals. Have you noticed that your highly intelligent friends tend to socialise less? Or are you the smart one that tends to pull away in order to focus on your own pursuits? Image credits: Getty Images

Mind

Female artists earn less than men. Coming from a diverse cultural background incurs even more of a penalty – but there is good news, too

Artists all over the world, regardless of their gender, earn <a href="https://www.sciencedirect.com/handbook/handbook-of-the-economics-of-art-and-culture">considerably less</a> than professionals in occupations requiring similar levels of education and qualifications. But there’s an additional income penalty for artists who are female. In an analysis of gender differences in the incomes of professional artists in Australia that <a href="https://australiacouncil.gov.au/advocacy-and-research/the-gender-pay-gap-among-australian-artists/">we undertook in 2020</a>, we found the creative incomes of women were 30% less than those of men. This is true even after allowing for differences in such things as hours worked, education and training, time spent in childcare and so on. This income penalty on women artists was greater than the gender pay gap of 16% experienced in the overall Australian workforce at the time. <a href="https://theconversation.com/screen-australia-celebrates-its-work-in-gender-equality-but-things-are-far-from-equal-122266">Some sectors</a> of the arts have tried to redress this problem. However, women continue to suffer serious and unexplained gender-based discrimination in the artistic workplace. Cultural differences are <a href="https://www.nber.org/papers/w27725">also known</a> to influence pay gaps in many countries. In new research <a href="https://australiacouncil.gov.au/advocacy-and-research/culture-and-the-gender-pay-gap-for-australian-artists">out today</a>, we considered whether cultural factors might also affect the gender pay gap of artists in Australia. In addition, we analysed the gender pay gap for remote Indigenous artists for the first time. <h2>A larger gap for women from a non-English speaking background</h2> In our <a href="https://australiacouncil.gov.au/advocacy-and-research/making-art-work/">2016 survey of 826 professional artists</a> working in metropolitan, regional and rural Australia, we asked participants if they came from a non-English speaking background. Only a relatively small proportion of artists – 10% – came from a non-English-speaking background, compared to 18% for the Australian labour force as a whole. A non-English-speaking background appears to carry an income penalty only for women artists, not for men. We found the annual creative earnings of female artists from a non-English-speaking background are about 71% of the creative incomes of female artists whose first language is English. But there is little difference between the corresponding incomes of male artists. Within the group of artists from language backgrounds other than English, the annual creative earnings of female artists are about half (53%) those of their male counterparts. By contrast, the ratio of female to male creative earnings among English-speaking background artists is 73%. These results suggest that women artists from a non-English-speaking background suffer a triple earnings penalty – from being an artist (and hence as a group earning less than comparable professionals), from their gender, and from their cultural background. Despite this earnings disadvantage, 63% of artists who identified as having a first language other than English thought their background had a positive impact on their artistic practice. Only 16% thought it had a negative impact. When artists were asked whether being from a non-English speaking background was a restricting factor in their professional artistic development, 17% of women answered “yes”, compared to only 5% of men from a similar background. Nevertheless, like their male colleagues, these women artists continue to celebrate their cultural background in their art. They contribute to the increasingly multicultural content of the arts in Australia, holding up a mirror to trends in Australian society at large. <h2>No gender gap in remote Indigenous communities</h2> For First Nations artists working in remote communities, a different picture emerges. For this research, we used results for remote communities in three regions of northern Australia drawn from our <a href="https://apo.org.au/node/257301">National Survey of Remote Aboriginal and Torres Strait Islander Artists</a>. The gender gap is not replicated among remotely practising First Nations artists. There are some minor variations in this finding for subgroups in different regions, depending in part on differences in the mix of visual and performing artists in the population. But whatever other differentials may exist between female and male earnings, they do not appear to be attributable to the sorts of systemic gender-based discrimination that affects the residual gender gap for other Australian artists. A possible reason relates to fundamental differences between the cultural norms, values and inherited traditions that apply in remote and very remote First Nations communities. Gender roles in Aboriginal and Torres Strait Islander communities have been <a href="https://anthrosource.onlinelibrary.wiley.com/doi/10.1525/can.1992.7.2.02a00020">described</a> by researchers as distinctively different, rather than superior or inferior. The importance of both women and men as bearers of culture has been clearly articulated. The unique cultural content of Aboriginal and Torres Strait Islander music, dance, visual art and literature is an essential feature of the work of these artists. These characteristics pass through to the marketplace, and there does not appear to be any obvious gender gap in the way the art from these remote communities is received. There is always differentiation between the art produced in different remote regions of Australia which varies depending on the complexities of different inherited cultural traditions. But there is no indication of any gender-based discrimination associated with these regional differences. Image credits: Getty Images This article originally appeared on <a href="https://theconversation.com/female-artists-earn-less-than-men-coming-from-a-diverse-cultural-background-incurs-even-more-of-a-penalty-but-there-is-good-news-too-195646" target="_blank" rel="noopener">The Conversation</a>.

Art

6 things that can happen to your body when you don’t drink enough water

While there is much talk about how much water one should drink per day (most experts suggest around two litres) have you ever thought what would actually happen to your body if you don’t get enough H2O? Here we chart six things that can go wrong if you don’t hit the recommended daily intake. 1. You're more likely to have health problems. Higher water intake has been linked to decreased chances of kidney stones, urinary and colon cancer, and heart attacks. 2. Your metabolism stagnates. In independent studies for his 2010 book The Water Secret (Wiley), Dr. Howard Murad found that a person's basal metabolic rate (the calories burned while at rest) speeds up as the body becomes more hydrated. 3. You'll have to think harder to complete the same tasks. At the Institute of Psychiatry at King's College London in 2011, scientists found that the brains of dehydrated teenagers had shrunk away from their skulls, and that when asked to play a problem-solving game, they performed just as well as those who drank enough, but engaged more of their brains to do so. (Drinking water restores the brain to its normal size.) 4. You eat more. A study of 45 adults funded by the Institute for Public Health and Water Research found that those who drank two eight-ounce glasses of water before each meal consumed 75 to 90 fewer calories while eating. (Over three months, water-drinkers lost an average of five pounds more than the dieters who were parched.) 5. You look more wrinkled. In researching his book, Dr. Murad also found that water plumps skin, fills in fine lines and wrinkles, and enlivens a dull complexion. 6. You're in a bad mood. In 2009, researchers at Tufts University in Medford, MA, asked members of the men's and women's crew teams to engage in 60 to 75 minutes of high-impact aerobic exercise without drinking enough water first. Others were properly hydrated. The dehydrated group was more likely to report feeling fatigued, confused, angry, depressed or tense. Image credits: Getty Images

Body

Mistletoe – famous for stolen holiday kisses – is a parasite that steals water and nutrients from other plants

A parasitic plant with potentially poisonous berries might not sound like something that would boost your Christmas decorations to the next level. But, botanically speaking, that’s what mistletoe is. There are some <a href="https://www.usgs.gov/news/featured-story/not-just-kissing-mistletoe-and-birds-bees-and-other-beasts">1,300 species of this evergreen plant worldwide</a>. They’re all parasitic or semiparasitic, meaning they can <a href="https://www.cornellpress.cornell.edu/book/9780801443718/diseases-of-trees-and-shrubs/#bookTabs=1">survive only on a host plant</a>. Rather than being rooted in the ground, they live on the branches of other trees and shrubs. Just <a href="http://dnrc.mt.gov/divisions/forestry/docs/assistance/pests/fidls/147.pdf">two types are native to North America</a>. Twelve species of the American mistletoe can be found distributed largely across the southern half of the U.S., mostly affecting deciduous trees in the East as well as some evergreens in the West. Sixteen species of the leafless dwarf mistletoe infect only trees in the pine family and are mostly found along the West Coast. The American mistletoe, the one used at Christmas in the U.S., is in the genus Phoradendron, which means “<a href="https://www.usgs.gov/news/featured-story/not-just-kissing-mistletoe-and-birds-bees-and-other-beasts">thief of the tree</a>” in Greek. It has green leaves and is capable of photosynthesis and so produces much of its own food. But American mistletoe also sucks water and other nutrients out of its host plant by sending rootlike structures <a href="https://doi.org/10.1016/B0-12-226865-2/00145-0">called haustoria</a> into the vascular tissue just under the bark of branches and twigs. These invading structures can live for many years inside a tree even if the mistletoe plant itself is removed. Mistletoes are what botanists call dioecious, meaning these plants have <a href="https://hortnews.extension.iastate.edu/2009/2-4/monoecious.html">separate male and female versions</a>. The females produce the fruits, called berries, which are generally white, but can be pink or reddish depending on the species. Birds widely distribute the seeds after eating the berries. Seeds of some species can also be <a href="https://www.fs.fed.us/rm/pubs_other/rmrs_1996_hawksworth_f001.pdf">shot out of the fruit</a> like a cannonball at up to 60 mph (100 kph) to a distance as far as 50 feet (15 meters). A sticky substance on the seeds helps them attach to any tree they land on until they germinate and begin to grow. In general, mistletoe won’t kill a tree unless it is heavily infested. Even then the tree doesn’t usually die from the mistletoe; most often death is an indirect effect of attacks from diseases or insects that take advantage of the stressed tree. Mistletoe’s parasitic ways can cause significant economic damage to forests industrially harvested for lumber. For a homeowner, though, it’s usually not necessary to control mistletoe – which is good, since getting rid of it can be difficult and takes patience and persistence. You can prune it out, being sure to get all those spreading haustoria under the host’s bark, or try chemical controls like the plant growth regulator ethephon. Maybe you’ll want to trim a sprig to decorate with during Christmastime. One of the most common traditions associated with mistletoe, <a href="https://time.com/5471873/mistletoe-kiss-christmas/">dating back at least to the 1700s</a>, is that anyone lingering beneath it would welcome a holiday kiss. Here in my home state of Oklahoma, mistletoe is our state floral emblem, apparently because it was the <a href="https://www.okhistory.org/publications/enc/entry.php?entry=MI047">only greenery available to put on graves</a> during the particularly hard winter of 1889. In other parts of the world, mistletoe is considered to bestow life and fertility, <a href="https://www.theholidayspot.com/christmas/history/mistletoe.htm">serve as a peace offering</a> and protect against poison. About poison: Mistletoe has a reputation as a poisonous plant. While the European species <a href="https://doi.org/10.5811/westjem.2012.8.12572">Viscum album is reportedly toxic</a>, <a href="https://doi.org/10.3109/15563659609013810">American mistletoe is not deadly</a>. Better to keep it away from little kids and pets, though, and if you are concerned, stick with artificial mistletoe for decorative purposes. Mistletoe is an important part of the ecosystem in the places where it grows in North America. Lots of birds rely on mistletoe berries as a food source, as do elk, deer, squirrels, chipmunks and even porcupines, which will also eat the leaves when other fresh foliage is scarce. Tangled clumps of mistletoe, traditionally referred to as witches’ brooms, provide nesting sites for birds, including spotted owls and Cooper’s hawks, and other animals. Three kinds of butterflies in the U.S. are entirely dependent on mistletoes. And it’s also an important nectar and pollen plant for honey bees and other native bees. So this parasitic plant plays a valuable role in both ecosystems and human traditions. If it grows near you, enjoy it because you probably wouldn’t be able to completely get rid of it anyway. And at Christmastime, it just may come in handy. Image credits: Getty Images This article originally appeared on <a href="https://theconversation.com/mistletoe-famous-for-stolen-holiday-kisses-is-a-parasite-that-steals-water-and-nutrients-from-other-plants-173555" target="_blank" rel="noopener">The Conversation</a>.

Home & Garden

One of Australia’s smallest homes sells for less than $100K

One of Australia’s most unusual homes, a tiny cottage that sits on stilts, seems to have found a new owner. A blue, one-bedroom house in Innisfail, Queensland, is currently under offer at $95,000 ($NZ 103,000), as reported by <a href="https://www.nine.com.au/property/homes/australias-tiny-blue-home-on-stilts-sells-for-95-thousand/c117bc64-2ea0-45e1-b145-98c47faaa7d3" target="_blank" rel="noopener">Nine</a>, after it was listed for $99,000 ($NZ 108,000) by Raine & Horne. With just 110 square metres of internal space, the property could be one of Australia’s smallest permanent homes. While <a href="https://www.raineandhorne.com.au/innisfail/properties/8-pelican-street-innisfail-4860-queensland" target="_blank" rel="noopener">the listing</a> describes it as having “plenty of life left in it” and “ready for a quick restoration”, the current state of the home’s interiors makes it uninhabitable, including holes in the walls with exposed wires, a shell of a kitchen, and loose wooden pailings on one side. The agent told the outlet that the house is on “stilts” after being moved from another local block and described it as a “potential gold mine”. The current owner reportedly had plans to build on the 1067-square-metre block, but these have since fallen through. An oven, bed, and a fridge with writing on it remain in the house, along with a single basin on the floor in one room. The space underneath the home is also partially enclosed, with an existing shower and the potential to be turned into a studio. Images: Raine & Horne Innisfail

Real Estate

Shooting of Imran Khan takes Pakistan into dangerous political waters

The attempted assassination of Imran Khan on November 3 has ushered Pakistan into another stage of political instability, with increased likelihood of further political violence. Imran <a href="https://www.bbc.com/news/world-asia-63496202" target="_blank" rel="noopener">has accused</a> Pakistan’s Prime Minister, Shehbaz Sharif, Interior Minister Sanaullah Khan and Major General Faisal of masterminding the attack. He has demanded these three be removed from their positions immediately. Failure to act, he <a href="https://twitter.com/PTIofficial/status/1588188079277232128?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1588188079277232128%7Ctwgr%5Ed5b3fd04e3131208521e14afe9946af45900de42%7Ctwcon%5Es1_c10&ref_url=https%3A%2F%2Fwww.thenews.com.pk%2Flatest%2F1006350-asad-umar-blames" target="_blank" rel="noopener">communicated through Asad Umer</a>, a senior member of his party, Pakistan Tehreek-e-Insaf (PTI), would result in demonstrations across the whole country, and “things would not continue as they have been”. The PTI’s Asad Umer said that two days ago, he had contacted Imran regarding threats to his safety. But Imran had stated: “We are engaged in jihad and we only need to trust Allah at this stage.” Building on this equivalence of the so-called “long march” with “jihad”, the PTI issued a <a href="https://twitter.com/Asad_Umar/status/1588399510614839296?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1588399510614839296%7Ctwgr%5E409bdb0bd9b63211810994ae51e1b298768da215%7Ctwcon%5Es1_c10&ref_url=https%3A%2F%2Fwww.thenews.com.pk%2Flatest%2F1006554-live-updates-day-8-pti-long-march-imran-khan-firing" target="_blank" rel="noopener">call for demonstrations</a> to start after Friday prayers on November 4. The Pakistan government <a href="https://www.thenews.com.pk/print/1006384-attack-on-imran-widely-condemned" target="_blank" rel="noopener">has responded</a> by condemning the assassination attempt. But <a href="https://www.thenews.com.pk/print/1006384-attack-on-imran-widely-condemned" target="_blank" rel="noopener">Minister Rana Sanaullah also told the PTI</a>: “It is [a] law of nature: those who ignite fire may also burn in it.” The national government has also demanded “the Punjab government constitute a Joint Investigation Team (JIT) to investigate the attack”. Others have raised questions about the security extended to the former prime minister in the province of Punjab, where a PTI government is in power. Conspiracy theories about the shooting also abound, including claims on social media that the attack was <a href="https://twitter.com/younus_bhoon/status/1588399845307711488?s=20&t=8c-lFy8oci8NGVAhcmNxxw" target="_blank" rel="noopener">orchestrated by PTI</a> to boost support for Imran. Only a few days ago, the former international cricketer turned politician had launched a second march within five months for haqiqi azadi (real freedom). Others accuse “external powers” of fomenting instability in the wake of Prime Minister Shehbaz Sharif’s <a href="https://www.aljazeera.com/news/2022/11/2/xi-jinping-assures-pakistani-pm-of-china-support" target="_blank" rel="noopener">visit to China</a>, where he met President Xi Jinping and revived the momentum for the China-Pakistan Economic Corridor (CPEC). Then there is the <a href="https://www.24newshd.tv/03-Nov-2022/attacker-says-was-angry-because-music-was-being-run-during-prayer-call" target="_blank" rel="noopener">reported admission</a> by the alleged assassin that he was motivated by religious fervour, as Imran’s march would not cease playing music even during the calls to prayer. Reminiscent of the grounds on which Mumtaz Qadri <a href="https://www.bbc.com/news/world-asia-35684452" target="_blank" rel="noopener">assassinated</a> the then governor of Punjab Salman Taseer, this explanation, with all its inconsistencies, locates the attempt outside the scope of political machinations. The reaction among Imran’s supporters has been swift. There have been demonstrations in all provinces of the country, with people <a href="https://www.youtube.com/watch?v=zFtMyPEJZYQ" target="_blank" rel="noopener">chanting the attack</a> had “crossed the red line” and they would lay their lives for Imran. This outpouring of support for Imran and anger towards the government has catapulted the country into increased instability, with the future now very uncertain. In the past, the instability might have been reined in by the Pakistan military, which has traditionally acted as custodian of law and order in the country. During the 75 years of Pakistan’s existence, the military has intervened directly or indirectly in politics when the country experienced instability. Even if its intervention was not approved of, politicians and society generally remained complacent and managed to work withing the framework outlined by the military. But in contemporary Pakistan, given the extent of political and social polarisation that has descended to a level not witnessed in the country’s history, the military may not be able to play this role. Already, Chief of Army Staff Qamar Javed Bajwa has claimed the <a href="https://www.news18.com/news/world/pakistan-army-chief-general-bajwa-to-retire-in-5-weeks-top-3-names-here-exclusive-6215221.html" target="_blank" rel="noopener">military would remain neutral</a>. Even if instability persists and the military decided to intervene, the reaction of Imran’s supporters would be very different from how people reacted to previous military interventions. The assassination attempt on Imran has removed a lot of self-imposed censorship by people. While people demonstrated outside the office of the Corps Commander of Peshawar, others have been recorded chanting that <a href="https://www.youtube.com/shorts/ga_22EwLXKg" target="_blank" rel="noopener">the uniform is behind acts of terrorism and hooliganism</a>. In the past, such comments were only openly made by Pashtoon Tahhafuz Movement (movement for the protection of Pashtoons). But now, such comments also allude to the <a href="https://www.bbc.com/news/world-africa-63372440" target="_blank" rel="noopener">recent killing</a> in Kenya of Pakistani journalist Ashraf Sharif, who had been a vocal critic of the military’s involvement in politics. It has been claimed the killing was orchestrated with the direct involvement of the military — a claim that prompted the director-general of Inter-Services Intelligence (ISI) to give a press conference refuting these claims. Such expressions of anger and open opposition to the military leadership would suggest the military would avoid direct interference. One possible avenue could be of imposing <a href="https://www.geo.tv/latest/430050-explainer-what-is-governors-rule-and-is-punjab-moving-towards-it" target="_blank" rel="noopener">governor rule</a> in Punjab and Khyber Pakhtunkhwa, but even that is unlikely to tamper the anger being felt by Imran’s supporters. Pakistan is fast moving into uncharted political terrain. This article originally appeared on <a href="https://theconversation.com/shooting-of-imran-khan-takes-pakistan-into-dangerous-political-waters-193937" target="_blank" rel="noopener">The Conversation</a>. Image: Getty

Legal

Gender pension gap: why women save less - and why that’s changing dramatically

One issue <a href="https://www.scottishwidows.co.uk/knowledge-centre/gender-pension-gap/">that has</a> attracted <a href="https://prospect.org.uk/article/what-is-the-gender-pension-gap/#:%7E:text=The%20gender%20pension%20gap%20is,gap%20that%20year%20(17.3%25).">growing attention</a> in <a href="https://www.aviva.co.uk/aviva-edit/your-money-articles/women-know-gender-pension-gap/">recent years</a> is the “gender pension gap” – the fact that on average, women have lower private pension wealth and lower income in retirement than men. But before rushing to conclusions about how to “fix” this, it is crucial to understand what lies behind any pension differences between men and women. There are three main potential drivers behind this phenomenon: <ol> <li> Different labour market experiences: the “<a href="https://www.ifs.org.uk/publications/10358">gender pay gap</a>”, and the fact that <a href="https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Duration_of_working_life_-_statistics#:%7E:text=In%202019%2C%20the%20estimated%20expected,aged%2015%20years%20and%20more">men have</a> longer paid working lives than women; </li> <li> Different investment strategies: when it comes to <a href="https://www.gov.uk/pension-types">defined contribution pensions</a>, <a href="https://s-h-w.com/news-articles">men choose</a> to invest in portfolios with a higher expected rate of return. </li> <li> Different saving rates: as <a href="https://www.ifs.org.uk/publications/15425">we investigate</a> below, men and women may also differ in how likely they are to be offered a pension in their job, or tend to work for employers that contribute more or less to a pension, or tend to make different contributions themselves. </li> </ol> Importantly, the role of these potential drivers will have changed over time for various reasons. Mothers <a href="https://www.ons.gov.uk/employmentandlabourmarket/peopleinwork/employmentandemployeetypes/articles/familiesandthelabourmarketengland/2019#:%7E:text=In%20April%20to%20June%202019%2C%20three%20in%20four%20mothers%20with,mothers%20in%20employment%20in%202000.">have increasingly participated</a> in the labour market over the years, for example. Final salary pensions have been reformed to career average schemes, which in particular reduced the generosity for long stayers and those with stronger pay growth, <a href="https://www.pensionspolicyinstitute.org.uk/sponsor-research/research-reports/2013/17-05-2013-the-implications-of-the-coalition-governments-public-service-pension-reforms/">affecting men</a> more than women. Also, <a href="https://www.pensionsadvisoryservice.org.uk/about-pensions/pensions-basics/automatic-enrolment">automatic enrolment</a> has been introduced for workplace pensions, which affected everyone’s participation in them. Gaps in pension income today may therefore reflect labour markets and pension arrangements from many years ago, and the gap in pension income for current working-age individuals may be quite different when they reach retirement. In an ongoing programme of work at the Institute for Fiscal Studies, funded by the <a href="https://www.nuffieldfoundation.org/">Nuffield Foundation</a>, we are examining in detail differences in pension saving rates between men and women that will contribute to a future “gender pension gap” for today’s working age individuals. <h2>Making sense of the gap</h2> In a <a href="https://www.ifs.org.uk/publications/15421">first publication</a>, we have documented differences in average pension saving between male and female employees before the introduction of <a href="https://www.pensionsadvisoryservice.org.uk/about-pensions/pensions-basics/automatic-enrolment">automatic enrolment</a> in 2012. We found that on average across all employees (whether saving in a pension or not), women of all ages actually contributed more as a proportion of their earnings each year than men. However, this was driven by the fact that women were more likely to work in the public sector, where contribution rates are typically higher. Examining average pension saving among men and women within each sector reveals a different pattern. The average saving rates of male and female employees were similar until around age 35 but then diverged, with average contributions continuing to increase with age for men but not changing for women. The graphs below unpick what was driving this pattern among private-sector employees in Great Britain (though the pattern was broadly similar for public-sector employees). It was caused by the extent to which men and women participated in a pension. The proportion of men and women saving anything in a private pension was similar until around age 30 but then diverged, with men increasingly likely to be saving in a pension as they get older, while women’s pension participation plateaued. On the other hand, average contribution rates for those saving in a pension were actually slightly higher as a share of earnings among women than men. Pension participation in overall savings <img src="https://oversixtydev.blob.core.windows.net/media/2022/10/graph-1.jpg" alt="" width="1280" height="720" /> Average contribution rates in pension savings <img src="https://oversixtydev.blob.core.windows.net/media/2022/10/graph-2.jpg" alt="" width="1280" height="720" /> What might have been driving differences in pension participation? The timing of the divergence in people’s lives mirrored the evolution of the gender gaps <a href="https://www.ons.gov.uk/employmentandlabourmarket/peopleinwork/earningsandworkinghours/bulletins/genderpaygapintheuk/2020">in pay</a>, <a href="https://www.ifs.org.uk/publications/13673">commuting</a> and <a href="https://www.ifs.org.uk/publications/14032">firm productivity</a>, and suggested that the arrival of children and related employment decisions was an important factor. So in our ongoing programme of research we are examining whether the gap in pension participation is associated with the arrival of children, and the extent to which female employees received a different pension offer from their employer, or made different saving decisions when presented with the same offer as male employees. <h2>Effect of automatic enrolment</h2> The introduction of automatic enrolment into workplace pensions has substantially changed pension-saving behaviour – in particular, substantially increasing pension participation among employees targeted by the policy. The graph below shows the proportion of male and female employees of different ages who were saving in a private workplace pension in 2012 and 2019 in Great Britain. The pattern in 2012 is represented by the two sets of dashed lines, with men again in blue and women in purple. It is similar to that estimated in the first graph in this article. But the pattern in 2019 is totally different. Rather than participation diverging at a particular age, women are now slightly less likely to be in a pension at all ages than men (but the level of participation among both is considerably higher). Automatic enrolment will therefore have fundamentally changed the nature of the gender gap in pension-saving rates going forwards. Pension participation 2019 vs 2012 <img src="https://oversixtydev.blob.core.windows.net/media/2022/10/graph-3.jpg" alt="" width="1280" height="720" /> This highlights the importance of examining gender differences in saving rates, rather than just accrued pension wealth or pension income. Focusing on the latter risks developing policies to fix a perceived problem that has already changed. Image credits: Getty Images This article originally appeared on <a href="https://theconversation.com/gender-pension-gap-why-women-save-less-and-why-thats-changing-dramatically-160648" target="_blank" rel="noopener">The Conversation</a>.

Retirement Income

Covid antiviral found to be “less effective” than placebo

Australia’s most widely-prescribed antiviral treatment for COVID-19 has been called into question seven months after it became available, after the results of a study into antiviral treatments found it was less effective than we initially thought. Molnupiravir, sold as Lageviro in Australia, has been prescribed to Aussies at a higher risk of severe illness from COVID-19 around 237,440 times since it was included in the Pharmaceutical Benefits Scheme (PBS) in March, according to the <a href="https://www1.racgp.org.au/newsgp/clinical/doubts-over-impact-of-key-antiviral-treatment" target="_blank" rel="noopener">RACGP</a>. But, preliminary data from <a href="https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4237902" target="_blank" rel="noopener">a study called PANORAMIC</a>, conducted by the University of Oxford, suggests that molnupiravir is not much better at reducing hospitalisation or deaths than those receiving standard care. Out of 25,000 adults included in the PANORAMIC trial, 103 of the 12,516 people taking molnupiravir were hospitalised or died in comparison to 96 of the 12,484 people not taking the drug. However, the study did find that those taking molnupiravir recovered more quickly. While the people participating in this trial were mostly vaccinated and healthy, <a href="https://www.researchsquare.com/article/rs-2115769/v1" target="_blank" rel="noopener">another study</a> involving nearly 20,000 adults over 40 - including 1000 being treated with molnupiravir and most having immunity from vaccinations of prior Covid infections - found that the rate of hospitalisation dropped by nearly half and deaths were reduced by nearly 75 percent among those aged over 65. The trial has confirmed long-held suspicions While the results of the PANORAMIC trial have caused a stir, with Australia’s National COVID-19 Clinical Evidence Taskforce saying it would review the study and probably update its recommendations, scientists have been sceptical of the effectiveness of molnupiravir for a while. Professor Peter White, who researches viruses, including their evolution and treatment with antivirals at the UNSW, Sydney, is one such sceptic. He tells OverSixty that we can expect to see similar results until a fundamental change is made to how we produce COVID-19 treatments. “The drugs that we’re using on coronavirus, like molnupiravir and paxlovid, both of those are actually designed for influenza, not for coronavirus. They were repurposed,” he explains. “And to me, that has never really worked well, like the drugs for HIV and HCV.” Professor White says this is because molnupiravir belongs to a particular class of drug called nucleotide analogues, which he says are the most common type of antiviral we use. “It’s a mimic of a natural RNA, what we call a nucleotide analogue, or a mimic of one of the four building blocks of life. In this case it’s an RNA molecule rather than DNA,” he explains. These drugs, which are used to treat hepatitis B and C, HIV, and herpes viruses among others, work by mimicking RNA and DNA molecules viruses use to replicate. “They tend to work by chain termination. The polymerase isn’t sophisticated enough to see that it’s not a true building block so they get incorporated into the new viral genomes,” Professor White explains. “So it incorporates into the growing RNA strand, but then nothing else can get incorporated and replication of the virus is stopped and you won’t get any replication from that strand.” But, a small percentage of nucleoside analogues don’t work like this, and molnupiravir is one of them. Instead, they introduce more mutations to the RNA than normal, which drives the virus into ‘error catastrophe’, otherwise known as lethal mutagenesis. “The virus ends up over-mutating and killing itself,” Professor White says. A comedy of errors isn’t that effective for viruses Antivirals that introduce mutations, such as molnupiravir, aren’t as effective as the chain terminating antivirals, according to Professor White, The only effective example, a drug developed to treat hepatitis C called ribavirin, came with severe side effects, including flu-like symptoms. But, it turns out that nucleoside analogues are quite specific too, primarily working on the virus they were designed for. “The antivirals that work really well have been designed against the virus that they were aimed to target,” Professor White explains. “And we haven’t had enough time to design really good coronavirus-specific antivirals. We’ve had enough time to repurpose Ebola and influenza drugs for coronaviruses, but most of the time it doesn’t work well. “And [molnupiravir] is another example of it not working.” History repeats itself Australia was one of the more aggressive purchasers of molnupiravir, with the <a href="https://www.smh.com.au/national/not-having-a-big-impact-covid-drug-fails-to-beat-placebo-in-major-trial-20221010-p5bohc.html" target="_blank" rel="noopener">Sydney Morning Herald</a> reporting that 301,000 courses of the antiviral were purchased in late 2021, before it was approved by the Therapeutic Goods Administration (TGA). But, this isn’t the first time we’ve secured large amounts of a drug that later proved less effective than we expected. “This is exactly what happened with Tamiflu (the antiviral used to treat influenza),” Professor White says. “Australia and many other countries bought millions of dollars worth of Tamiflu, which never got used. And then five years later, some clinical trials that weren’t published got released … and it was shown that they released the good (results) in the earlier trials and this drug isn’t as effective as we first thought.” While we might be scrambling to find the next best treatment as soon as we can, Professor White says that developing effective drugs takes time - and that drugs specifically targeting Covid’s polymerase and protease enzymes will be the most effective. “That’s the problem we’ve got at the moment. We’ve got repurposed drugs for other viruses, and maybe they work a little bit and they’ve been approved because we’ve got nothing else as yet,” he says. “But this is not the end of the story. This is not the true, good drug that we could actually find. “We could do a lot better, but we’re going to have to wait a couple of years.” Image: Getty Images

Body

Does cooking bacon in water make it taste better

A rumour on the internet has suggested the key to juicier, crispier bacon is submerging it in cold water and bringing it to the boil. But does this theory have legs? Well, the idea at least seems to check out. The difference between “good” and “bad” bacon generally comes down to the rendering of the fat from cooking to too long or too quickly. But when you cook it with the cold-water method, bringing the cold water to the simmer, cooking it away completely, you theoretically cook the fat away without drying the bacon, and once the water’s gone all you have to do is brown the meat. <iframe width="560" height="315" src="https://www.youtube.com/embed/2guC4Badq2s" frameborder="0" allowfullscreen=""></iframe> <a href="http://www.news.com.au/lifestyle/food/eat/internet-cooking-test-should-you-cook-bacon-in-water/news-story/a4ac7d3e60033861c0a625ef9638c526" target="_blank">News.com.au</a> recently put this to test, cooking a control and putting it up against the new bacon cooking method, “The ‘new’ method had produced much drier, darker bacon. It was crispier as promised, but in a way that made it less enjoyable to eat. It had developed the consistency reminiscent of beef jerky. “Even worse, this method seemed to have leached a lot of the bacon’s salt content out into the water before gluing it back to the outside of the bacon as it evaporated, making the bacon much saltier to taste.” So, what do you think? Are you going to experiment with this new bacon-cooking method, or stick to what you know works? Let us know in the comments below.

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What is micellar water and how does it work?

How much weight do you actually need to lose? It might be a lot less than you think

Trying to spend less on food? Following the dietary guidelines might save you $160 a fortnight

Eye-watering price tag for "remarkable" first class Titanic menu

Does running water really trigger the urge to pee? Experts explain the brain-bladder connection

Princess Diana's dresses fetch an eye-watering sum at auction

The cost of living is biting. Here’s how to spend less on meat and dairy

Fleetwood Mac legend’s eye-watering fortune revealed

"Get out of the water!" Huge shark spotted at crowded beach

Five easy ways to use less water at home – and not just in a drought

King Charles’ eye-watering net worth revealed

Why smart people prefer fewer friends

Female artists earn less than men. Coming from a diverse cultural background incurs even more of a penalty – but there is good news, too

6 things that can happen to your body when you don’t drink enough water

Mistletoe – famous for stolen holiday kisses – is a parasite that steals water and nutrients from other plants

One of Australia’s smallest homes sells for less than $100K

Shooting of Imran Khan takes Pakistan into dangerous political waters

Gender pension gap: why women save less - and why that’s changing dramatically

Covid antiviral found to be “less effective” than placebo

Does cooking bacon in water make it taste better

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